Datasets for the RNA-seq analysis of TBHP-treated NPCs with or without PG@MBC hydrogel co-culture

The differentially expressed genes (DEGs) were determined using the DESeq2 package, with an adjusted p-value < 0.05 and the absolute value of log2 fold change ≥ 1. The enrichment analyses of DEGs were performed using the SRplot and Sangerbox platforms. Mitochondria-related genes (MRGs) were based on a previous study (DOI: 10.1186/s12967-023-04033-6), while ferroptosis-related genes (FRGs) were sourced from the FerrDb database. The overlap between DEGs and both MRGs and FRGs was delineated as key genes, which were used to construct the PPI network via the STRING database. This network was then imported into Cytoscape and analyzed with the Cytohubba plugin.