Discovery and Characterization of Genetic Risk Loci in Sjogren's syndrome

The Sjogren's Genetics Network (SGENE) is an international collaboration focused on identifying and understanding the genetic variations that influence Sjogren's pathology. Collectively, SGENE collaborators from 26 different sites (5 in the United States; 21 in foreign countries) have recruited a large cohort of geographically diverse participants of European ancestry. Participants underwent extensive medical assessment for Sjogren's Disease (formerly Sjogren's Syndrome) using internationally accepted American-European Consensus Group (AECG) classification criteria or the American College of Rheumatology/European League Against Rheumatism classification criteria. Recruitment, sample collection, and genotyping were performed at unique SGENE sites in compliance with local institutional... (for more see dbGaP study page.)