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EED in complex with PRC2 allosteric inhibitor compound 11

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5h25
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EED in complex with PRC2 allosteric inhibitor compound 11 Descriptor: 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED Authors: Zhao, K, Zhao, M, Luo, X, Zhang, H. Deposit date: 2016-10-14 Release date: 2017-01-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy J. Med. Chem., 60, 2017
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2016-10-14
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