Crystal structure of c-Met in complex with AMG 337
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5eyd
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of c-Met in complex with AMG 337 Descriptor: 6-[(1~{R})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one, Hepatocyte growth factor receptor Authors: Whittington, D.A, Long, A.M. Deposit date: 2015-11-24 Release date: 2016-02-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity. J.Med.Chem., 59, 2016
创建时间：
2015-11-24
