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Expression profile of Yeast Frataxin Mutants

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NIAID Data Ecosystem2026-03-07 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44871
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Yeast Frataxin Homologue 1 has been involved in oxidative stress and iron-sulfur biogenesis within the mitochondria. We have investigated the expression profile of conditional Yfh1 mutants. Yfh1 depletion leads to activation of iron uptake and repression Two strains were used: WT (strain W303-1A) and tetYFH1 (YFH1 gene under the control of a tet promoter regulatable with doxycycline). We compared the expression profile of tetYFH1 vs tetYFH1 + 10h doxycycline. As control we also compared W303-1A vs W303-1A
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2013-10-17
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