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Identification and investigation of depression-related molecular subtypes in inflammatory bowel diseases and the anti-inflammatory mechanisms of paroxetine

NIAID Data Ecosystem2026-03-14 收录

肠道微生物群与抑郁症

抗抑郁治疗机制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP409474 数据链接链接失效反馈

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资源简介：

We examined the effects of two antidepressants, paroxetine and fluoxetine, on intestinal flora in mice under an inflammatory load in the gut. (Fecal samples)

应用场景：

创建时间：

2023-02-06

肠道微生物群与抑郁症

发酵食品

BackgroundGut microbiota-based therapeutic strategies, such as probiotic and prebiotic preparations, may benefit mental health. However, commonly consumed fermented and prebiotic-containing foods have

NIAID Data Ecosystem60

Dihydroartemisinin protects mice from CUMS-induced depression-like behaviors by regulating gut microbes

肠道微生物群与抑郁症

DHA抗抑郁机制

Background. Depression is one of the most common forms of psychopathology, which is associated with gut microbiota dysfunction. Dihydroartemisinin (DHA) has been shown to regulate gut microbiota and a

NIAID Data Ecosystem30

Fluoxetine and ketamine trigger the p75NTR proteolytic pathway and enhance extinction memory and brain plasticity through p75NTR

抗抑郁治疗机制

神经营养因子

Pharmacologically diverse antidepressants were recently described to bind to TrkB and drive a positive allosteric modulation of endogenous BDNF. Although neurotrophins such as BDNF can bind to the

Figshare2024-02-15 更新20

Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol

转运蛋白结构

抗抑郁治疗机制

Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ... Authors: Wang, H, Goua

Protein Data Bank Japan2024-02-28 更新50

The role microglia in electroconvulsive threapy (ECT) in depressed-like mice. The role microglia in electroconvulsive threapy (ECT) in depressed-like mice

神经免疫调控

抗抑郁治疗机制

Recent studies implicate microglia alterations in the pathogenesis and pathophysiology of depression. For example, chronic unpredictable stress (CUS) in mice can cause degeneration of microglia and de

NIAID Data Ecosystem30

Identification and investigation of depression-related molecular subtypes in inflammatory bowel diseases and the anti-inflammatory mechanisms of paroxetine

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