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HIV-1 protease in complex with the inhibitor bea403

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Protein Data Bank Japan2024-02-07 更新2026-03-21 收录
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HIV-1 protease in complex with the inhibitor bea403 Descriptor: HIV-1 PROTEASE, N,N-[2,5-O-DI-2-FLUORO-BENZYL-GLUCARYL]-DI-[1-AMINO-INDAN-2-OL] Authors: Unge, T. Deposit date: 2000-01-25 Release date: 2002-06-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy Eur.J.Biochem., 271, 2004
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2000-01-25
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