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Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells

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A single cell transcriptional profile of fibroblasts in the lung, ectopic bones and fetal limbs. Fibroblasts were FACS-isolated from the lung, fetal limbs and ectopic bones formed in recipient mice transplanted with lung universal fibroblasts of Ubc-GFP mise. 5000-10000 cells were loaded onto 10X Genomic Chromium Single Cell Expression Solution version 3. platform. cDNA was sequenced by Illumina NovaSeq 6000.

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