DLS-data for nanoparticle characterisation of 1,4-DHP and calix[4]arenes

Characterisation of two-component nanoformulations comprised from cationic amphiphilic 1,4-DHP as one component and the appropriate cationic amphiphilic calix[4]arene as another component at mol% ratios of 100/0, 75/25, 50/50, 25/75, and 0/100; starting from single the appropriate calix[4]arene (100/0) in the first sample and single 1,4-DHP (0/100) in the last sample. The obtained results - hydrodynamic diameters of the main population of nanoparticles, polydispersity index and z-potential of nanoparticles formed by 1,4-DHP/calix[4]arene compositions in aqueous medium determined by the DLS method are presented. Dynamic light scattering (DLS) instrument Zetasizer Nano ZSP (Malvern Panalytical Ltd.) with Malvern Instruments Ltd. Software 7.12 was used for evaluation of self-assembling properties of pure cationic 1,4-DHP and calix[4]arene derivatives and characterisation of obtained nanoparticles formed by them in different ratios or individually.

本研究对由阳离子两亲性1,4-DHP和相应的阳离子两亲性杯[4]芳烃组成的二元纳米制剂进行了表征，其中所述制剂在摩尔比100/0、75/25、50/50、25/75及0/100下制备；从首个样品中仅含有适当的杯[4]芳烃（100/0）出发，至最后一个样品中仅含有1,4-DHP（0/100）进行制备。所获得的结果包括：由1,4-DHP/杯[4]芳烃组成的纳米粒子在水介质中的主粒子群的水动力直径、多分散性指数和z电位，这些参数均通过动态光散射（DLS）法测定。本研究采用动态光散射仪器Zetasizer Nano ZSP（Malvern Panalytical Ltd.）及其配套软件7.12对纯阳离子1,4-DHP及其杯[4]芳烃衍生物的自组装性能进行了评估，并对其在不同比例或单独制备所得的纳米粒子的特性进行了表征。