Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control
The change in acetylation is displayed as both percent change (%) and log (base2) values for the C1 animal relative to D1. Each value represents the average of two replicates ChIP-qPCR assays.
Imaging data across Embryonic Stages from Figure S7 of "Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila" by Fitz-James et al.