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Directed Evolution of an Adenine Base Editor with Increased Activity and Context Compatibility

NIAID Data Ecosystem2026-05-01 收录

碱基编辑器优化

定向进化

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243181 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-09-15

生物催化

定向进化

Biocatalysis is now a mature field, both in the laboratory and industrial scale. This approach counts on enzyme high selectivity, biodegradability, elegant control over the outcome of reaction conditi

DataCite Commons2021-03-25 更新50

Ketoreductase CpKR mutant - M2

定向进化

手性药物合成

Ketoreductase CpKR mutant - M2 Descriptor: Mutant M2 of ketoreductase CpKR, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Chen, C, Pan, J, Xu, J.H. Deposit date: 2022-10-14 Releas

Protein Data Bank Japan2026-03-04 更新30

Substrate structure and computation guided engineering of a lipase for omega-3 fatty acid selectivity

定向进化

脂肪酸选择性催化

Enrichment of omega-3 fatty acids (ɷ-3 FAs) in natural oils is important to realize their health benefits. Lipases are promising catalysts to perform this enrichment, however, fatty acid specificity o

NIAID Data Ecosystem30

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 4 Wild Type

定向进化

蛋白质晶体

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 4 Wild Type

NIAID Data Ecosystem40

Crystal Structure Analysis of the dienelactone hydrolase (E36D, C123S) mutant- 1.5 A

蛋白质晶体学

定向进化

Crystal Structure Analysis of the dienelactone hydrolase (E36D, C123S) mutant- 1.5 A Descriptor: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION Authors: Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.

Protein Data Bank Japan2023-10-25 更新30

Directed Evolution of an Adenine Base Editor with Increased Activity and Context Compatibility

资源简介：

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