Microarray analysis of lymphocytes isolated from healthy donors ex-vivo exposed to alpha particle radiation

The purpose of this study was to identify genes that are modulated by alpha particle radiation Cell types were independently exposed to alpha particle radiation using Americium-241 discs (0.9Gy/hr) at a dose range from 0-1.5 Gy. Twenty-four hours post-exposure cells were harvested and RNA was extracted and subjected to microarray analysis. Expression profiling by array analysis-Sample set, 0, 0.5, 1.0, 1.5 Gy (n=12), analysed 24h post exposure