H2A.Z marks the 5' end of genes

In S. cerevisiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent heterochromatin to prevent its ectopic spread在酿酒酵母（Saccharomyces cerevisiae）中，组蛋白变体H2A.Z被沉积于沉默型异染色质侧翼的常染色质区域，以阻止该异染色质发生异位扩散。