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RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication

NIAID Data Ecosystem2026-03-14 收录

泛素化调控

锥虫kDNA复制机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA922953 数据链接链接失效反馈

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资源简介：

CRISPR/Cas9 genetic screens reveal an unexpected negative genetic interaction between RNF4 and USP7 in DNA replication.

应用场景：

创建时间：

2023-01-11

锥虫kDNA复制机制

cohesin功能

Cohesin is established by two parallel pathways during DNA replication. Chromosome associated cohesin is converted to cohesive structures and this depends on four protein associated with the replisome

NIAID Data Ecosystem30

Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed nucleotide occupancy

蛋白质结构解析

锥虫kDNA复制机制

Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed nucleotide occupancy Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Pajak,

Protein Data Bank Japan2025-11-26 更新20

Nuclear cGAS ubiquitylation

泛素化调控

先天免疫信号通路

Model of cGAS ubiquitylation.

Figshare2024-02-29 更新10

Smc5/6 functions jointly with the Sgs1-Top3-Rmi1 DNA resolvase to complete chromosome replication at natural pause sites

锥虫kDNA复制机制

染色体复制

Smc5/6 is essential for genome structural integrity by yet unknown mechanisms. Here we find that Smc5/6 co-localizes with the DNA crossed-strand resolvase Sgs1-Top3-Rmi1 (STR) complex at genomic regio

NIAID Data Ecosystem30

Additional file 1: of SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression

前列腺癌分子机制

泛素化调控

Table S1. SPOP mutation status, ATF2 IHC scores in 90 cases of prostate cancer specimens and the associated clinical information. Table S2. Positive hits of the yeast two-hybrid screening. (XLSX 2194

Figshare2024-03-04 更新10

RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication

资源简介：

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