Health condition pair associations.

(A) Complete results from the unstratified, undirected comorbidity network analysis. (B-D) Results from age-stratified analyses for Young Adult, Mature Adult, and Senior dogs respectively. There is no table for the puppy cohort as no comorbid pairs were identified. (E) Results from directed network analysis showing temporal relationships between conditions occurring within a 12-month window. For all analyses, health condition pairs are shown with their names, corresponding body system classifications, test statistic, expected values and variance under the null, and p-values (unadjusted and adjusted). (XLSX)