five

Running and locomotor plasticity

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP184881
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In precious studies, we established an animal model with the genetic absence of the CST by conditionally inactivating Celsr3 in corticospinal motor neurons (Emx1-Cre;Celsr3f/- mice) and found that spontaneous plasticity of the motor network partially contributed to functional recovery.However, Emx1-Cre;Celsr3f/- mice still behave movement abnormalities compared to the littermate control. In this study, we assess whether voluntary exercise fosters functional improvement and its potential mechanisms.
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2020-03-01
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