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PARP1 inhibition at R loops selectively kills spliceosome mutant leukemias by triggering transcription-replication conflicts

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NIAID Data Ecosystem2026-05-01 收录
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The goal of this study is to determine the gene expression and alternative splicing changes in U2AF1-WT vs. U2AF1-S34F cells, and SRSF2-WT and SRSF2-P95H mutant K562 cells.

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2023-11-08
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