Crystal structure of SARS-CoV-2 main protease A191T mutant in complex with an inhibitor Nirmatrelvir
收藏Protein Data Bank Japan2024-11-13 更新2026-04-04 收录
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Crystal structure of SARS-CoV-2 main protease A191T mutant in complex with an inhibitor Nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER Authors: Bulut, H, Hattori, S, Hayashi, H, Hasegawa, K, Li, M, Wlodawer, A, Tamamura, H, Mitsuya, H. Deposit date: 2024-03-04 Release date: 2024-04-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structural and virologic mechanism of the emergence of resistance to M pro inhibitors in SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 121, 2024
创建时间：
2024-03-04
