JAK1 kinase (JH1 domain) in complex with compound 20
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JAK1 kinase (JH1 domain) in complex with compound 20 Descriptor: (1R,3R)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8H)-yl)cyclohexanol, Tyrosine-protein kinase JAK1 Authors: Eigenbrot, C, Steffek, M. Deposit date: 2012-04-04 Release date: 2012-07-04 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. J.Med.Chem., 55, 2012
创建时间：
2012-04-04
