Intra Class Correlation coefficients for all T1DM participants (n = 26).

ICC: Intra-class correlation coefficient (2, 1). Inter refers to inter-observer reproducibility, intra to intra-observer reproducibility. The manual protocol included manual image selection and manual image analysis. The semi-automated protocol included manual image selection and automated analysis. The fully-automated protocol included automated image selection and automated analysis. CNFL, corneal nerve fibre length. CNFD, corneal nerve fibre density. CNBD, corneal nerve branch density.* Manual protocol ICC have been presented in a previous publication and are shown here for comparison.† For the 13-member sub-population without DSP, inter-observer ICC for CNFLFully-Automated was 0.78(0.30,0.93) and intra-observer ICC for CNFLFully-Automated was 0.84(0.55,0.95). For the 13-member sub-population with DSP, the inter-observer ICC for CNFLFully-Automated was 0.65(0.05,0.89) and intra-observer ICC for CNFLFully-Automated was 0.72(0.31,0.90). Comparisons of these ICC were not statistically significant.Intra Class Correlation coefficients for all T1DM participants (n = 26).