BRD2_Bromodomain2 complex with pyrrolopyridone compound 27
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6viy
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BRD2_Bromodomain2 complex with pyrrolopyridone compound 27 Descriptor: 4-[2-(2,6-dimethylphenoxy)-5-(ethylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 2 Authors: Longenecker, K.L, Park, C.H, Qiu, W. Deposit date: 2020-01-14 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.904 Å) Cite: Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain. J.Med.Chem., 63, 2020
创建时间：
2020-01-14
