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Guidance for the Derivation of an Acute Reference Dose

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Organisation for Economic Co-operation and Development2026-03-28 收录
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The objective of this document is to provide guidance on how to derive an Acute Reference Dose (ARfD). It outlines a stepwise approach on how to best use all available toxicological data, and what to do if more data are needed on the refinement of the toxicological data base with regard to the acute effects of the compound being investigated or an...
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