Equilibrium and kinetic constants involved in the inhibition of AcPhe-puromycin synthesis by CAM dimers^a.

aData denote the mean ± S.E. values obtained from three independently performed experiments, with two replicates per experiment. bThe kon/koff ratio was calculated through Equation: kon/koff = Ki/Ki* − 1, [11]. cThe individual values of kon and koff were calculated by nonlinear regression fitting of the kinetic data to Equation: k eq =k off +k on [I] Ki 1+ [S] KS + [I] Ki dData taken from Xaplanteri et al., [6] eIn the range of concentrations 1–20 μM, compound 8 was not active in inhibiting the puromycin reaction. Equilibrium and kinetic constants involved in the inhibition of AcPhe-puromycin synthesis by CAM dimersa.