Tomm70
收藏rgd.mcw.edu2025-03-23 收录
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ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN negative regulation of cell growth involved in cardiac muscle cell development; positive regulation of protein targeting to mitochondrion; protein targeting to mitochondrion; PARTICIPATES IN alpha-helical insertion pathway of mitochondrial protein import; beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import; ASSOCIATED WITH Cardiomegaly; congestive heart failure; Experimental Diabetes Mellitus; FOUND IN mitochondrial outer membrane; mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol
编码一种表现出分子适配器活性的蛋白质(同源物);参与心脏肌细胞发育中细胞生长的负向调控;正向调控蛋白质靶向线粒体;蛋白质靶向线粒体;参与线粒体蛋白质导入的α-螺旋插入途径;线粒体蛋白质导入的β-桶状途径;线粒体蛋白质导入的载体途径;与心肥大、充血性心力衰竭、实验性糖尿病有关;存在于线粒体外膜、线粒体膜(同源物)、线粒体(同源物)中;与2,4-二硝基甲苯、2,6-二硝基甲苯、3-氯丙烷-1,2-二醇相互作用。
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