Amastigote susceptibility results of the in vivo resistance selection procedure to PMM-MIL combination therapy.
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No difference was observed between IC50 of the wild-type (ITMAP263 WT) and the strain that was exposed five times to high concentrations of PMM and MIL (ITMAP263 PMM/MIL). Exposure to PMM alone (ITMAP263 PMM) revealed a significant susceptibility decrease (indicated in bold)[14]. (ND: not done).
创建时间：
2017-05-25
