Additional file 2 of Unraveling the metabolomic architecture of autism in a large Danish population-based cohort

Additional file 2: Table S1. All metabolites associated with autism (p < 0.05) in logistic regression model 1, adjusted for age at sampling, season of birth and gestational age. Proof of annotations from GNPS, SIRIUS, MS2LDA and notes for manual annotations are presented. Table S2. Odds ratios and p-values for logistic regression model 1, model 2 and model 3. All significant (p < 0.05) metabolites in model 1 are shown. Table S3. Associations with autism stratified by age of diagnosis. Early indicates autism diagnosis < 6 years old and late >  = 6 years old. Results are from logistic regression model 1. Table S4. Autism associations for cyclic dipeptides cyclo(Leu-Pro) and cyclo(Pro-Val) when included as covariates in the same logistic regression model (model 1). Table S5. Metabolite class enrichment analysis. P-values are calculated using Fisher's exact test. Table S6. Baseline characteristics description of participants from the Malmö Diet and Cancer Study (MDC) and the Malmö Offspring Study (MOS). Table S7. Correlations between 5-AVAB and dietary intake in the Malmö Diet and Cancer Study (MDC) and the Malmö Offspring Study (MOS) stratifed by sex. Table S8. Top 500 SNPs from genomewide association study of 5-AVAB in the Malmö Diet and Cancer Study. Table S9. Relative standard deviations (%) in repeated injections of quality control (QC) samples for 16 metabolites. QC samples consist of pooled adult blood spotted on filter paper. Table S10. Top 500 SNPs from genomewide association study of 5-AVAB in the neonatal cohort. Table S11. Top 500 SNPs from genomewide association study of cLP in the neonatal cohort.