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Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-{4-[(4R)-4-hydroxy-6-oxo-4-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-yl]piperidin-1-yl}-4-(trifluoromethyl)pyridine-3-carbonitrile, NICKEL (II) ION, ... Authors: Manthei, K.A, Chang, L, Tesmer, J.J.G. Deposit date: 2018-10-25 Release date: 2018-12-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol. Elife, 7, 2018
创建时间:
2018-10-25
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