OPC_RN_LN_dataset.csv

Public anonymized data deposition for the publication:

Spatially-aware clustering improves AJCC-8 risk stratification performance in oropharyngeal carcinomas; Guadalupe Canahuate, Andrew Wentzel, Abdallah S.R. Mohamed, Lisanne V. van Dijk, David M. Vock, Baher Elgohari, Hesham Elhalawani, Clifton D. Fuller, G. Elisabeta Marai. Oral Oncology, Volume 144, 2023, 106460. ISSN 1368-8375.

https://doi.org/10.1016/j.oraloncology.2023.106460.

https://www.sciencedirect.com/science/article/pii/S1368837523001562

Description of data:

Comprises as cohort of anonymized/deidentified data from 675 HPV+ OPC patients that were treated at MD Anderson Cancer Center between 2005 and 2013 with curative intent IMRT, retrospectively collected under IRB approval. Risk stratifications incorporating patient radiometric data and lymph node metastasis patterns via an anatomically-adjacent representation with hierarchical clustering were identified. These clusterings were combined into a 3-level patient stratification and included along with other known clinical features in a Cox model for predicting survival outcomes, and logistic regression for toxicity, using independent subsets for training and validation.