Crystal structure of SARS-CoV-2 Mpro-H172Y mutant in complex with nirmatrelvir
收藏Protein Data Bank Japan2025-09-03 更新2026-03-28 收录
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Crystal structure of SARS-CoV-2 Mpro-H172Y mutant in complex with nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, Non-structural protein 11 Authors: El Kilani, H, Hilgenfeld, R. Deposit date: 2023-01-24 Release date: 2025-08-06 Last modified: 2025-09-03 Method: X-RAY DIFFRACTION (2.65 Å) Cite: 13b-K and Nirmatrelvir Resistance Mutations of SARS-CoV-2 Main Protease: Structural, Biochemical, and Biophysical Characterization of Free Enzymes and Inhibitor Complexes Crystals, 15, 2025
创建时间：
2023-01-24
