首页/数据集/The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development. The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development

The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development. The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development

NIAID Data Ecosystem2026-03-10 收录

B细胞发育

VDJ重组

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA385811 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2017-05-08

B细胞发育

信号转导分析

We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis. Overall design: CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+

NIAID Data Ecosystem100

Phospholipase C? pathway-dependent mTOR signaling controls IL-7-mediated early B cell development

B细胞发育

免疫通路分析

We examined the global gene expression profile of PLC?1/PLC?2 double-deficient CLPsand B cell progenitors by RNA-seq analysis. Overall design: CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+

NIAID Data Ecosystem60

Mta2, a component of the NuRD complex, regulates B cell development and cooperates with OCA-B in controlling the pre-B to immature B cell transition (RNA-Seq)

B细胞发育

转录组学分析

The goal of this study is to compare NGS-derived mouse B cell RNA profiling in Mta2 KO, Ocab KO, and double KO mice Pro-B, Pre-B, and small pre-B cell RNA profiles from control, Mta2 KO, OcaB KO, or d

NIAID Data Ecosystem20

Targeted Capture VDJ and Translocation Detection in Myeloma Cell Lines. Targeted Capture VDJ and Translocation Detection in Myeloma Cell Lines

多发性骨髓瘤遗传学

VDJ重组

Multiple myeloma is a disease of malignant plasma cells characterized by oncogenic translocations in immunoglobulin genes and a clonal V(D)J signature, which can both be used to track disease over tim

NIAID Data Ecosystem60

BCR and TLR-induced IRF1 promotes T cell independent B cell responses by supporting Notch2 dependent Marginal Zone B cell development

B细胞发育

T细胞非依赖性抗体应答

The prototypic interferon (IFN)-inducible transcription factor, IRF1, not only controls expression of IFN genes but also regulates T cell and macrophage fate specification and function. We show that I

NIAID Data Ecosystem40

The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development. The deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B cell development

资源简介：

相关数据集