Rbfox2 is necessary for cardiovascular development
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135152
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Purpose: The goal of this study is to investigate the role of Rbfox2, an RNA binding protein in cardiovascular development. Methods: RNA-Seq splicing analysis of mouse embryonic heart at embryonic day 9.5, isolated from control and genetic deletion of either one or both allels of Rbfox2 using Nkx2-5 Cre. Rbfox2 was deleted from early cardiovascular linease by crossing Rbfox2 floxed mice with Nkx2-5 Cre mice. Effect of Rbfox2 knock-down on alternative splicing and mRNA expression was compared between Control, heterozygous knock-out and homozygous knock-out.
创建时间：
2022-03-02
