Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

ChEBI2016-08-08 更新2026-07-12 收录

肌生成调控

mRNA翻译调控

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Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

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2016-08-08

Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch

果蝇生物学

mRNA翻译调控

The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first tw

NIAID Data Ecosystem90

Source data for Figure 2 and Supplementary Figure 2

mRNA翻译调控

细胞基因表达

Source Data for Figure 2 and Supplementary Figure 2Fraction of translating, tethered mRNA per cell for Fig. 2DTranslation intensity of single mRNA for one experimental day for Fig. 2EIntensity of repo

Figshare2021-04-20 更新70

HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA. HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA

肌生成调控

转录后调控

Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscr

NIAID Data Ecosystem40

A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation (RNA-seq). Mus musculus

肌生成调控

转录组分析

The transcriptional activator MyoD serves as a master controller of myogenesis. Often in partnership with Mef2, MyoD binds to the promoters of hundreds of muscle genes in proliferating myoblasts, yet

NIAID Data Ecosystem70

mRNA seq of total and polysome associated mRNAs in three different conditions. mRNA seq of total and polysome associated mRNAs in three different conditions

mRNA翻译调控

RNA测序

We report on how the presence or absence of a 18 nt long ribosome-bound RNA affects the translation in S. cerevisiae. We observe that translation of all mRNAs is downregulated when the RNA is present.

NIAID Data Ecosystem40

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

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