Output of GTDB-tk, providing a summary of its taxonomic annotation of all isolate and type strain genomes included in this study, as well as listing up to 100 genomes identified as close relatives based on ANI.

The standardized bacterial taxonomy established by GTDB, and used by GTDBtk, merges the genus Spirillospora with many species typically recognised as belonging to the genus Actinomadura in NCBI and LPSN (Approved Lists) [80]. All members of this new merged genus are named Spirillospora based on the use of Spirillospora albus as the type species for the genus in GTDB. This includes Actinomadura madurae, which is renamed to Spirillospora madurae in GTDB. All isolates reported as belonging to the Spirillospora genus by GTDBtk were positively identified as Spirillospora madurae (Actinomadura madurae). As such, we elected to continue to use the established genus name for Actinomadura madurae to describe the taxonomic assignment of these isolates throughout the manuscript [81], as this name is still recognised as the valid species epithet in LPSN (Approved Lists) and NCBI, and more broadly recognisable in the actinomycetoma research community.
(XLSX)