Chiral-Anion-Dependent Inversion of Diastereo- and Enantioselectivity in Carbonyl Crotylation via Ruthenium-Catalyzed Butadiene Hydrohydroxyalkylation
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https://figshare.com/articles/dataset/Chiral_Anion_Dependent_Inversion_of_Diastereo_and_Enantioselectivity_in_Carbonyl_Crotylation_via_Ruthenium_Catalyzed_Butadiene_Hydrohydroxyalkylation/2457511
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资源简介：
The ruthenium catalyst generated in situ from H2Ru(CO)(PPh3)3, (S)-SEGPHOS,
and a TADDOL-derived
phosphoric acid promotes butadiene hydrohydroxyalkylation to form
enantiomerically enriched products. Notably, the observed diastereo-
and enantioselectivity is the opposite of that observed using BINOL-derived
phosphate counterions in combination with (S)-SEGPHOS,
the same enantiomer of the chiral ligand. Match/mismatch effects between
the chiral ligand and the chiral TADDOL-phosphate counterion are described.
For the first time, single-crystal X-ray diffraction data for a ruthenium
complex modified by a chiral phosphate counterion are reported.
创建时间：
2012-12-26
