Eukaryotic Translation Elongation

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>本事件系通过计算方法从另一物种已证实的事件中推断而来。该推断基于PANTHER的同源映射。简而言之，对于所有参与物理实体（包括输入、输出和催化剂）均具有对应同源/旁系同源（对于复合体而言，至少75%的组分必须具有映射）的反应，将推断至其他物种。此外，对于这些事件，还推断出高级别事件，以便于更便捷的导航。<p>关于Reactome中事件推断的更多细节和注意事项，请参阅<a href='/electronic_inference_compara.html' target = 'NEW'>此处</a>。关于PANTHER的详细信息，请参阅<a href='http://www.pantherdb.org/about.jsp' target='NEW'>此处</a>。

搜集汇总

背景与挑战

背景概述

该数据集描述了酿酒酵母（Saccharomyces cerevisiae）中的真核生物翻译延伸过程，这是一个通过计算推断从人类等其他物种推导出来的生物学事件。它详细说明了翻译延伸的机制，包括核糖体、tRNA和延伸因子（如eEF1A和eEF2）的相互作用，涉及肽键形成和mRNA移位，细胞定位在细胞质，并关联到GO生物过程'翻译延伸'。