Functional roles of RUNX1::ERG in K562 myeloid leukemia cells [K562_RUNX1-ERG]

To investigate the functional significance and transcriptional impacts associated with RUNX1::ERG, we overexpressed the fusion gene in K562 myeloid leukemia cells and analysed global gene expression changes using RNA-seq. Differential gene expression profiling analysis of RNA-seq data for K562 cells expressing RUNX1::ERG and the empty vector control.