Proportion of live cells after 48 hours of pemetrexed treatment.

Live cells after treatment, normalized to untreated control cells. Results are mean values from at least three independent experiments, with corresponding standard deviation. Mesothelioma cell lines arranged with increasing length/width ratios, with epithelioid and sarcomatoid cell lines in bold and Jurkat cells as positive control. Asterisks denote a significant differences between the treated and control cells using a paired student’s t-test with one-tailed p-values (p<0.05).