Effects of Dabigatran and Rivaroxaban on TG in PPP (high tissue factor).

TG, thrombin generation triggered by 5 pM recombinant tissue factor; PPP, platelet-poor plasma; Dabi, dabigatran; Riva, rivaroxaban; LT, lag time; TTP, time to peak of TG; PH, peak height of TG; ETP, endogenous thrombin generation potential.
Data are shown as the mean ± SD. * P<0.05, ** P<0.01, and *** P<0.001 vs. control.
§indicates that, since TG curves did not come down to the baseline within 60 min, ETP values were calculated by setting the start tail at 60min.