Using a Stem Cell-Based Signature to Guide Therapeutic Selection in Cancer

ChEBI2010-10-16 更新2026-07-21 收录

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Using a Stem Cell-Based Signature to Guide Therapeutic Selection in Cancer

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2010-10-16

Deconvolution of breast tumors for optimal chemotherapy selection

肿瘤微环境

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Extensive work in pre-clinical models has shown that microenvironmental cells influence many aspects of cancer cell behavior including metastatic potential and their sensitivity to therapeutics. In th

NIAID Data Ecosystem40

Table1_Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types.XLSX

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药物重定位

Cervical cancer is the fourth most commonly diagnosed cancer worldwide and, in almost all cases is caused by infection with highly oncogenic Human Papillomaviruses (HPVs). On the other hand, inflammat

NIAID Data Ecosystem20

WP229 - Irinotecan pathway - Homo sapiens

药物代谢

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This pathway shows the biotransformation of the chemotherapy prodrug irinotecan to form the active metabolite SN-38, an inhibitor of DNA topoisomerase I. SN-38 is primarily metabolized to the inactive

NIAID Data Ecosystem10

Table_5_Characterization of heterogeneous metabolism in hepatocellular carcinoma identifies new therapeutic target and treatment strategy.xlsx

肝细胞癌代谢亚型

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BackgroundMetabolic reprogramming is a well-known hallmark of cancer. Systematical identification of clinically relevant metabolic subtypes of Hepatocellular carcinoma (HCC) is critical to understand

NIAID Data Ecosystem40

Circulating Tfh1 (cTfh1) cell numbers and PD1 expression are elevated in low-grade B-cell non-Hodgkin’s lymphoma and cTfh gene expression is perturbed in marginal zone lymphoma

淋巴瘤免疫微环境

细胞生物标志物

CD4+ T-cell subsets are found in the tumour microenvironment (TME) of low-grade B-cell non-Hodgkin’s lymphomas such as marginal zone lymphoma (MZL) or follicular lymphoma (FL). Both numbers and archit

Figshare2018-01-03 更新10

Using a Stem Cell-Based Signature to Guide Therapeutic Selection in Cancer

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