Mir221

ENCODES an ncrna that exhibits mRNA base-pairing translational repressor activity (ortholog); INVOLVED IN cellular response to glucose stimulus; cellular response to nerve growth factor stimulus; negative regulation of osteoblast differentiation; ASSOCIATED WITH breast cancer; diabetes mellitus; hepatocellular carcinoma; FOUND IN RISC complex (ortholog); synapse (ortholog); INTERACTS WITH 2-acetamidofluorene; aflatoxin B1; atrazine

编码一种表现出mRNA基序配对翻译抑制因子活性（同源）的非编码RNA；参与细胞对葡萄糖刺激的应答；细胞对神经生长因子刺激的应答；成骨细胞分化的负调控；与乳腺癌、糖尿病、肝细胞癌相关；存在于RISC复合体（同源）中、突触（同源）中；与2-乙酰胺基荧光素、黄曲霉毒素B1、阿特拉津相互作用。