Chronic activation of hepatic Nrf2 has no major effect on fatty acid and glucose metabolism in adult mice

ChEBI2016-09-01 更新2026-07-12 收录

肝脏代谢调控

Nrf2信号通路

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资源简介：

Chronic activation of hepatic Nrf2 has no major effect on fatty acid and glucose metabolism in adult mice

创建时间：

2016-09-01

Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling

Nrf2信号通路

小分子药物

The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeostasis in response to oxidative stress by the regulation of multiple cytoprotective genes. Without stre

NIAID Data Ecosystem50

Liver transcriptome data of Esr1 knockout male rats reveals altered expression of genes involved in carbohydrate and lipid metabolism.

肝脏代谢调控

基因表达分析

Estrogens are traditionally considered to be female sex steroid hormones and most of the studies examining estrogen regulation of metabolic function in the liver have been conducted in females. Howeve

NIAID Data Ecosystem40

Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels [lxr_chip]

肝脏代谢调控

转录因子功能分析

Transitions from a fed to a fasted state are common in mammals. The liver orchestrates adaptive responses to feeding/fasting by transcriptionally regulating metabolic pathways of energy usage and stor

NIAID Data Ecosystem30

The SWI/SNF subunit Dpf2 licenses Nrf2-dependent gene expression to enforce multilineage control of inflammation [CUT&RUN]

炎症与表观遗传调控

Nrf2信号通路

Purpose: Multi-omics characterization of the consequences of deleting the SWI/SNF subunit Dpf2 in the transcriptome (RNAseq), accessibility of the genome (ATACseq) and binding of SWI/SNF subunits (CUT

NIAID Data Ecosystem50

Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets

仔猪营养管理

肝脏代谢调控

The objective of this study was to reveal the effects of early life lactoferrin intervention on the liver metabolism in the suckling piglets. Sixty newborn piglets with an average initial body weight

NIAID Data Ecosystem40

Chronic activation of hepatic Nrf2 has no major effect on fatty acid and glucose metabolism in adult mice

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