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Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist

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Protein Data Bank Japan2024-10-09 更新2026-04-19 收录
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Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist Descriptor: 5-(3-bicyclo[4.2.0]octa-1,3,5-trienyl)-1,2,3,6-tetrahydropyridine, Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Xu, J, Fink, E.A, Shoichet, B.K, Du, Y. Deposit date: 2021-12-04 Release date: 2022-09-28 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure-based discovery of nonopioid analgesics acting through the alpha 2A -adrenergic receptor. Science, 377, 2022
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2021-12-04
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