Substrate-Controlled, One-Pot Synthesis: Access to Chiral Chroman-2-one and Polycyclic Derivatives
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https://figshare.com/articles/dataset/Substrate_Controlled_One_Pot_Synthesis_Access_to_Chiral_Chroman_2_one_and_Polycyclic_Derivatives/2072476
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资源简介：
Based on the appropriate choice of
electrophiles, one-pot, multicomponent,
enantioselective domino reactions have been realized which contain
a five-step sequence and provide highly efficient access to potentially
bioactive chroman-2-one derivatives as a single diastereoisomer with
excellent enantioselectivities and in high yields. This new strategy
could significantly improve the previous protocol by directly starting
from commercial 2-hydroxybenzaldehydes rather than preformed lactols,
which have to be synthesized in several additional steps.
创建时间：
2016-02-12
