mRNA expression profiles in primary microglia cells treated with R848, IFN-α, and R848+ IFN-α. mRNA expression profiles in primary microglia cells treated with R848, IFN-α, and R848+ IFN-α

Using RNA-seq, we have reported signaling crosstalk between IFN-α and R848 at the level of transcriptomes highlighting synergsitic gene expression dynamics upon different receptors signaling in microglia cells Overall design: Comparative study of the effects of control versus R848, IFN-α and R848+IFN-α treated PM cells, were generated by deep sequencing on an Illumina HiSeq 2500 (101 cycles PE lane).