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Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor Descriptor: 2,4-dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile, Tyrosyl-DNA phosphodiesterase 2 Authors: Hornyak, P, Pearl, L.H, Caldecott, K.W, Oliver, A.W. Deposit date: 2016-03-31 Release date: 2016-05-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochem.J., 473, 2016
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2016-03-31
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