Cryo-EM structure of human gamma-secretase in complex with RO4929097
收藏Protein Data Bank Japan2025-07-23 更新2026-04-19 收录
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Cryo-EM structure of human gamma-secretase in complex with RO4929097 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Guo, X, Li, H, Kai, U, Yan, C, Lei, J, Zhou, R, Shi, Y. Deposit date: 2023-08-08 Release date: 2024-08-14 Last modified: 2025-07-23 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of human gamma-secretase inhibition by anticancer clinical compounds. Nat.Struct.Mol.Biol., 32, 2025
创建时间：
2023-08-08
