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Glycan and gene chip analysis of purified osteoclast cell populations

ChEBI2011-04-29 更新2026-07-21 收录

破骨细胞分化机制

糖组学与基因表达谱

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28947 数据链接链接失效反馈

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资源简介：

Glycan and gene chip analysis of purified osteoclast cell populations

应用场景：

创建时间：

2011-04-29

巨噬细胞分化

破骨细胞分化机制

Colony Stimulating Factor 1(CSF1) is known to promote osteoclast progenitor survival but its role in regulating osteoclast differentiation and mature osteoclast function are less well understood. Macr

NIAID Data Ecosystem60

RNAseq from macrophages and osteoclasts from wild-type and TRAP deficient bone cell reporter mice

骨细胞RNA测序

破骨细胞分化机制

Osteoclasts are multinucleated giant cells generated by the fusion of precursors in response to stimulation with macrophage colony stimulating factor (MCSF) and receptor activator of NF-kB ligand (RAN

NIAID Data Ecosystem30

ZMAT1 promotes osteoclast formation and bone loss through TRIM46 mediated YAP1 degradation.

破骨细胞分化机制

骨质疏松症靶点

Osteoclasts and osteoblasts play a critical role in bone remodeling, and their dysregulation leads to pathological bone loss. However, precise regulation of their differentiation remains not fully elu

NIAID Data Ecosystem10

TGFÃ reprograms TNF stimulation of macrophages towards osteoclastogenesis [RNA-seq]

破骨细胞分化机制

炎症性骨丢失

TNF plays a key role in inflammation and bone resorption. However, the mechanisms regulating TNF-mediated osteoclastogenesis remain largely unclear because its direct osteoclastogenic ability is weak.

NIAID Data Ecosystem50

Additional file 1 of Elucidating the role of RBM5 in osteoclastogenesis: a novel potential therapeutic target for osteoporosis

骨质疏松症靶点

破骨细胞分化机制

Additional file 1: Table S1. The primers used for RT-qPCR analysis.

NIAID Data Ecosystem20