TAp73 functions through posttranscriptional codes in brain multiciliogenesis
收藏Alliance of Genome Resources2026-08-01 收录
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Although being essential to respiratory and reproductive tracts multiciliogenesis, TAp73 is dispensable for multiciliogenesis in the ventricles. TAp73 KO is accompanied by dramatic changes in ciliogenic microRNAs miR34bc and miR449 family members, suggestin TAp73 functions partially thorugh posttranscriptional nodes in brain ciliogenesis. Total RNA from WT and TAp73 KO lateral ventricles/CP were isolated by phenol/chloroform method.
