Human Immunology Project Consortium Repository

The Human Immunology Project Consortium (HIPC) Dashboard is a web-application supporting the storage and dissemination of immune signatures curated from published literature. Using computational analysis of large-scale experimental data from high-throughput systems biology approaches coupled with detailed clinical phenotyping in well-characterized human cohorts, the HIPC aims to identify molecular “signatures” that correlate with the outcomes of vaccinations, adjuvants or natural infections in humans. To facilitate dissemination of this information to the scientific community the Consortium has developed the “HIPC Dashboard”, a web interface that provides access to consistently annotated immune signatures generated by HIPC activities as well as curated from the literature.

人类免疫学项目联盟（Human Immunology Project Consortium，HIPC）仪表盘是一款支持存储与分发从已发表文献中整理得到的免疫特征（immune signatures）的Web应用程序。该联盟通过对高通量系统生物学方法产生的大规模实验数据开展计算分析，并结合经过充分表征的人类队列的详细临床表型数据，旨在识别与人类疫苗接种、佐剂使用或自然感染结局相关的分子特征。为推动此类信息向科学界公开传播，该联盟开发了“HIPC仪表盘”这一Web界面，可访问由HIPC项目生成以及从文献中整理得到的经统一注释的免疫特征。

搜集汇总

背景与挑战

背景概述

人类免疫学项目联盟（HIPC）是一个研究网络，旨在通过分析高通量系统生物学数据并结合临床表型，识别与人类疫苗接种、佐剂或自然感染结果相关的分子‘签名’。该联盟开发的HIPC Dashboard是一个网络界面，为科学界提供由HIPC活动生成和文献整理的免疫签名数据，以促进信息传播。