Measurements of biochemical markers in CoPP-pretreated cardiomyocytes subjected to hypoxia.

The release of LDH and CK after 2 h of hypoxia was lower in the group treated with CoPP compared with the untreated group. SnPP administration abolished the beneficial effect of CoPP pretreatment. The value of 100% was given to the level of LDH or CK released from untreated cells not subjected to hypoxia. Data are means of at least 3 replicates in 5 separate experiments. Values are means ± SD (LDH $p<0.01 vs. normoxia, #p<0.01 vs. hypoxia, *p<0.01 vs. hyp +CoPP, CK$p<0.01 vs. normoxia, #p<0.01 vs. hypoxia, *p<0.01 vs. hyp +CoPP).